The RA3.3A1/6.1 monoclonal antibody reacts with mouse B220 also known as CD45R. B220 is a 220 kDa transmembrane protein tyrosine phosphatase expressed on B cells and some subsets of T and NK cells. B220 plays a critical role in TCR and BCR signaling and is commonly used as a B cell marker. The RA3.3A1/6.1 antibody is commonly used for in vivo B cell depletion.
| Isotype | Rat IgM |
| Recommended Isotype Control(s) | InVivoMAb polyclonal rat IgG(BE0094) |
| Recommended InVivoPure Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer(IP0070) |
| Immunogen | Mouse RAW 112 lymphosarcoma cells |
| Reported Applications |
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| Endotoxin |
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| Purity |
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| Formulation |
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| Sterility | 0.2 μM filtered |
| Production | Purified from tissue culture supernatant in an animal free facility |
| Purification | Protein G |
| Storage | The antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze. |
| RRID | AB_1107651 |



