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主营:抗体类,InVivo Mab抗体,InVivo Plus抗体,InVivo纯稀释缓冲液,ReadyTag抗体,融合蛋白
℡ 4000-520-616
℡ 4000-520-616
BioXcell/InVivoPlus anti-mouse 4-1BB (CD137)/DISCOUNTED ACADEMIC OR NON PROFIT: 5MG/BP0169-A005mg
产品编号:BP0169-A005mg
市  场 价:¥10500.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$525.00
品      牌: BioXcell
公      司:BioXcell
公司分类:
BioXcell/InVivoPlus anti-mouse 4-1BB (CD137)/DISCOUNTED ACADEMIC OR NON PROFIT: 5MG/BP0169-A005mg
商品介绍

About InVivoMAb anti-mouse IL-12 p40

The C17.8 antibody reacts with mouse p40 also known as IL-12β. p40 is a 40 kDa subunit of IL-12 and IL-23. IL-12 is a heterodimeric cytokine composed of subunits IL-12α p35 and IL-12β p40. The p40 subunit of IL-12 also combines with p19, a protein that shows no biological activity by itself, to form IL-23. IL-12 is secreted by activated monocytes, macrophages, and dendritic cells while IL-23 is secreted by activated dendritic cells and epithelial cells. IL-12 plays roles in T lymphocyte differentiation, IFNγ production, and NK cell cytotoxicity. The C17.8 antibody has been shown to neutralize both IL-12 and IL-23 bioactivity.

InVivoMAb anti-mouse IL-12 p40 Specifications

Isotype

Rat IgG2a, κ

Recommended Isotype Control(s)InVivoMAb rat IgG2a isotype control, anti-trinitrophenol(BE0089)
Recommended InVivoPure Dilution BufferInVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

Recombinant mouse IL-12 p70

Reported Applications
  • in vivo IL-12p40 neutralization
  • p40 affinity chromatography
  • Immunoprecipitation
  • ELISA
  • Flow cytometry
  • Western blot
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Storage

The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

RRID

AB_1107698

Molecular Weight

150 kDa

品牌介绍

在Bio X Cell,我们是免疫学研究的忠实拥护者。我们的团队致力于以优惠的价格提供高质量的抗体。这样,您可以花费更少的时间进行故障排除实验,而将更多的时间用于处理最重要的事情,例如刺激4-1BB或阻断LAG-3来促进抗肿瘤T细胞反应,或者只享受实验室外的生活。

自豪地位于美国新罕布什尔州

我们所有的产品都是在新罕布什尔州黎巴嫩的工厂现场制造的。这使我们能够对制造过程进行严格控制,从而使产品成为超纯,低内毒素抗体的金标准。



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